We studied comparison of high school education between Myanmar and Japan by using the textbooks of chemistry in high school, visiting schools and study tours. In both countries, the level of curriculum contents common. The contents of the textbooks are arranged systematically in order to the laws, principles, basic concepts, examples and explanations. There is a little difference in the explanation of each topic, some are details in Myanmar, but some are details in Japan. School chemistry can teach the students about the influence of chemical knowledge on human society.